Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799382 | 0.78 | ADRA2A (0.46) | CES2CES1KDM4ELMNAL3MBTL1 | |
| SCHEMBL23436586 | 0.78 | CES2 (0.45) | CES2CES1KDM4ELMNAL3MBTL1 | |
| SCHEMBL18087488 | 0.77 | CES2 (0.48) | CES2CES1KDM4ELMNAL3MBTL1 | |
| SCHEMBL1408599 | 0.77 | CES2 (0.58) | CES2CES1KDM4ELMNAL3MBTL1 | |
| SCHEMBL22357260 | 0.76 | KDM4E (0.61) | CES2CES1KDM4ELMNAL3MBTL1 | |
| Methyl Alcohol SCHEMBL28478481 | 0.75 | ALDH1A1 (0.58) | CES2CES1KDM4ELMNAL3MBTL1 | |
| SCHEMBL9461486 | 0.75 | — | — | |
| SCHEMBL19085486 | 0.74 | CES2 (0.50) | CES2CES1KDM4ELMNAL3MBTL1 | |
| SCHEMBL21953560 | 0.74 | KDM4E (0.48) | CES2CES1KDM4ELMNAL3MBTL1 | |
| SCHEMBL172761 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294332-B2 | Functionalized siloxane materials | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-05-21 | — | — | US | disclosed |
| US-20180016401-A1 | FUNCTIONALIZED SILOXANE MATERIALS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-01-18 | — | — | US | disclosed |