Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21368556 | 0.88 | XIAP (0.32) | — | |
| SCHEMBL19785915 | 0.88 | XIAP (0.32) | — | |
| Hydrochloric Acid SCHEMBL21354253 | 0.87 | XIAP (0.32) | — | |
| Hydrochloric Acid SCHEMBL21354290 | 0.87 | XIAP (0.32) | — | |
| Hydrochloric Acid SCHEMBL21354254 | 0.87 | XIAP (0.32) | — | |
| Hydrochloric Acid SCHEMBL21354250 | 0.87 | XIAP (0.32) | — | |
| Hydrochloric Acid SCHEMBL21354282 | 0.87 | XIAP (0.32) | — | |
| Hydrochloric Acid SCHEMBL21354252 | 0.87 | XIAP (0.32) | — | |
| SCHEMBL22383754 | 0.83 | RORC (0.47) | — | |
| SCHEMBL22383780 | 0.83 | ALDH1A1 (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484880-B1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA AS (DK) | 2020-09-02 | — | — | EP | disclosed |
| WO-2018011201-A1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2018-01-18 | — | — | WO | disclosed |