Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785950 | 0.69 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2HPGDCYP1A2 | |
| SCHEMBL10767715 | 0.66 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2HPGDCYP1A2 | |
| SCHEMBL11791658 | 0.65 | GPR35 (0.59) | TAS1R3TAS1R1TAS1R2CXCR1CXCR2 | |
| SCHEMBL28718277 | 0.64 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2CYP1A2CYP2C19 | |
| SCHEMBL29670968 | 0.64 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2CYP1A2CYP2C19 | |
| SCHEMBL19779431 | 0.64 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2HPGDCYP1A2 | |
| SCHEMBL27371005 | 0.62 | MEN1 (0.50) | TAS1R3TAS1R1TAS1R2CYP1A2CYP2C19 | |
| SCHEMBL27370682 | 0.62 | TAS1R3 (0.37) | TAS1R3TAS1R1TAS1R2HPGDCYP1A2 | |
| SCHEMBL19785829 | 0.62 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2HPGDCYP1A2 | |
| SCHEMBL19785982 | 0.61 | KDR (0.55) | TAS1R3TAS1R1TAS1R2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013789-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION (US) | 2018-01-18 | — | — | WO | disclosed |