Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785829 | 0.90 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2KDRCASP3 | |
| SCHEMBL19785982 | 0.84 | KDR (0.55) | TAS1R3TAS1R1TAS1R2KDRCASP3 | |
| SCHEMBL19785763 | 0.81 | KDR (0.37) | TAS1R3TAS1R1TAS1R2KDRBTK | |
| SCHEMBL19779431 | 0.79 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2CASP3HPGD | |
| SCHEMBL19785768 | 0.77 | PDCD1 (0.43) | TAS1R3TAS1R1TAS1R2KDRMEN1 | |
| SCHEMBL19785953 | 0.75 | KDR (0.45) | KDRCASP3KDM4EL3MBTL1MEN1 | |
| SCHEMBL396661 | 0.74 | CFTR (0.63) | MEN1KMT2ACFTR | |
| SCHEMBL19785758 | 0.72 | KDR (0.43) | KDRKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL19779672 | 0.72 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2HPGDCYP1A2 | |
| SCHEMBL19785949 | 0.69 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2CASP3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013789-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION (US) | 2018-01-18 | — | — | WO | disclosed |