SCHEMBL197860

SCHEMBL197860

C=CCC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 1/20 0.56
HTT P42858 1/20 0.53
KMT2A Q03164 3/20 0.44
CES1 P23141 3/20 0.43
AKT1 P31749 1/20 0.42
MEN1 O00255 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
SRC P12931 1/20 0.40
MAPT P10636 3/20 0.39
HPGD P15428 2/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PTPN1 P18031 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL9749754 0.94 TSHR (0.50) ALDH1A1TSHRHTTKMT2ACES1
SCHEMBL8723027 0.91 ALDH1A1 (0.47) ALDH1A1TSHRHTTKMT2ACES1
SCHEMBL10398398 0.91 ALDH1A1 (0.47) ALDH1A1TSHRHTTKMT2ACES1
Ether SCHEMBL9750209 0.89 ALDH1A1 (0.46) ALDH1A1TSHRHTTKMT2ACES1
SCHEMBL11586635 0.88 ALDH1A1 (0.45) ALDH1A1TSHRHTTKMT2ACES1
SCHEMBL11588492 0.87 ALDH1A1 (0.44) ALDH1A1TSHRHTTKMT2ACES1
SCHEMBL11586797 0.85 TSHR (0.46) ALDH1A1TSHRHTTKMT2ACES1
SCHEMBL245184 0.84 TSHR (0.44) ALDH1A1TSHRHTTCES1LMNA
SCHEMBL7385780 0.83 ALDH1A1 (0.67) ALDH1A1TSHRHTTKMT2AAKT1
SCHEMBL6944126 0.83 ALDH1A1 (0.67) ALDH1A1TSHRHTTKMT2AAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1809 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240213-A Negative photosensitive polyimide precursor and composition thereof 深圳先进电子材料国际创新研究院 2024-06-25 CN claimed
CN-118244583-A Negative photosensitive polyimide precursor resin composition 深圳先进电子材料国际创新研究院 2024-06-25 CN claimed
US-11998621-B2 Transparent, fracture-tough polymerization resins for the production of dental shaped bodies IVOCLAR VIVADENT AG (LI) 2024-06-04 US claimed
CN-116909100-B Photosensitive polyimide precursor composition 深圳先进电子材料国际创新研究院 2024-03-19 CN claimed
CN-116909100-A Photosensitive polyimide precursor composition 深圳先进电子材料国际创新研究院 2023-10-20 CN claimed
CN-116482933-A Negative photosensitive polyimide precursor resin composition 深圳先进电子材料国际创新研究院 2023-07-25 CN claimed
CN-109988312-B Polyamide acid ester, preparation method, negative polyimide composition and application 深圳先进技术研究院 2023-04-11 CN claimed
CN-115160569-B Photosensitive polyamic acid ester resin, resin composition and electronic component 明士(北京)新材料开发有限公司 2022-12-27 CN claimed
CN-115300400-A Transparent, fracture-tough polymeric resins for the production of dental molded bodies 义获嘉伟瓦登特公司 2022-11-08 CN claimed
CN-115160569-A Photosensitive polyamic acid ester resin, resin composition and electronic component 明士(北京)新材料开发有限公司 2022-10-11 CN claimed
US-10702815-B2 Nanostructured fibrous membranes for membrane distillation THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2020-07-07 US claimed
CN-106233205-B Photosensitive element, laminate, permanent mask resist, method for producing same, and method for producing semiconductor package 日立化成株式会社 2020-06-23 CN claimed
CN-105849641-B Photosensitive resin composition, photosensitive element, method for forming resist pattern, and method for producing printed wiring board 日立化成株式会社 2019-12-13 CN claimed
CN-109988312-A A kind of poly amic acid ester, preparation method and negative polyimide composition and application 深圳先进技术研究院 2019-07-09 CN claimed
CN-109946925-A A kind of compound is promoting the application in polyimides low-temperature setting, polyimide precursor composition and application thereof 深圳先进技术研究院 2019-06-28 CN claimed
CN-109867787-A A kind of polyimide precursor, resin combination, cured film and preparation method thereof 深圳先进技术研究院 2019-06-11 CN claimed
US-20170326486-A1 NANOSTRUCTURED FIBROUS MEMBRANES FOR MEMBRANE DISTILLATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2017-11-16 US claimed
US-4387139-A Elastomeric, ethylenically unsaturated polyurethanes and radiation polymerizable mixtures containing such polyurethanes KALLE, NIEDERLASSUNG DER HOECHST AG (DE) 1983-06-07 US claimed
US-4086299-A WITH UNSATURATED CARBOXY ACID ICI AUSTRALIA LIMITED (AU) 1978-04-25 US claimed
US-3990958-A Radiation polymerization of triallylamines using a non-polar, non-hydroxylic solvent ICI AUSTRALIA LIMITED (AU) 1976-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11998621-B2 Transparent, fracture-tough polymerization resins for the production of dental shaped bodies MMAB, VCL, BOLA2; BOLA2B ALDH1A1 1495/4885TSHR 1668/4885HTT 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.