Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197860 | 0.94 | ALDH1A1 (0.56) | TSHRALDH1A1CES1HTTSRC | |
| Ether SCHEMBL9750209 | 0.90 | ALDH1A1 (0.46) | TSHRALDH1A1CES1HTTSRC | |
| SCHEMBL11586635 | 0.88 | ALDH1A1 (0.45) | TSHRALDH1A1CES1HTTSRC | |
| SCHEMBL10398398 | 0.88 | ALDH1A1 (0.47) | TSHRALDH1A1CES1HTTSRC | |
| SCHEMBL8723027 | 0.88 | ALDH1A1 (0.47) | TSHRALDH1A1CES1HTTSRC | |
| SCHEMBL11588492 | 0.87 | ALDH1A1 (0.44) | TSHRALDH1A1CES1HTTSRC | |
| SCHEMBL11586797 | 0.85 | TSHR (0.46) | TSHRALDH1A1CES1HTTSRC | |
| SCHEMBL245184 | 0.84 | TSHR (0.44) | TSHRALDH1A1CES1HTTCYP3A4 | |
| SCHEMBL11091632 | 0.83 | CES1 (0.53) | TSHRALDH1A1CES1HTTSRC | |
| SCHEMBL11585318 | 0.83 | TSHR (0.43) | TSHRALDH1A1CES1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228145-B1 | POLYPHOTOINITIATORS | LOCTITE CORPORATION (US) | 1992-03-18 | — | — | EP | disclosed |
| EP-0228145-A1 | Polyphotoinitiators | LOCTITE CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4587276-A | Polyphotoinitiators | LOCTITE CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |
| US-4081492-A | POLYEPOXIDE BINDERS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-28 | — | — | US | disclosed |
| US-3937722-A | PHOTOSENSITIZERS, IRRADIATION POLYMERIZATION, CROSSLINKING | BAYER AG (DT) | 1976-02-10 | — | — | US | disclosed |