Ether

Ether

SCHEMBL9750209

C=CCC(O)(C(=O)c1ccccc1)c1ccccc1.CCOCC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.44
CES1 P23141 2/20 0.43
SRC P12931 1/20 0.40
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 3/20 0.37
MAPK1 P28482 1/20 0.37
POLB P06746 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
AKT1 P31749 1/20 0.35
LMNA P02545 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL9749754 0.90 TSHR (0.50) ALDH1A1TSHRHTTCES1SRC
SCHEMBL197860 0.89 ALDH1A1 (0.56) ALDH1A1TSHRHTTCES1SRC
SCHEMBL11588492 0.89 ALDH1A1 (0.44) ALDH1A1TSHRHTTCES1SRC
SCHEMBL10398398 0.87 ALDH1A1 (0.47) ALDH1A1TSHRHTTCES1SRC
SCHEMBL11586797 0.87 TSHR (0.46) ALDH1A1TSHRHTTCES1SRC
SCHEMBL245184 0.85 TSHR (0.44) ALDH1A1TSHRHTTCES1MAPK1
SCHEMBL11586635 0.84 ALDH1A1 (0.45) ALDH1A1TSHRHTTCES1SRC
SCHEMBL11586950 0.84 TSHR (0.43) ALDH1A1TSHRHTTCES1LMNA
SCHEMBL11585318 0.84 TSHR (0.43) ALDH1A1TSHRHTTCES1LMNA
SCHEMBL8723027 0.84 ALDH1A1 (0.47) ALDH1A1TSHRHTTCES1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0228145-B1 POLYPHOTOINITIATORS LOCTITE CORPORATION (US) 1992-03-18 EP disclosed
EP-0228145-A1 Polyphotoinitiators LOCTITE CORPORATION (US) 1987-07-08 EP disclosed
US-4587276-A Polyphotoinitiators LOCTITE CORPORATION (US) 1986-05-06 US disclosed
US-4503208-A HYDROSTLATION OF ACRYLIC ESTER OF ACETYLENIC ALCOHOL LOCTITE CORPORATION (US) 1985-03-05 US disclosed
US-4141806-A MULTISTAGE, TEMPERATURE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4107012-A COATINGS, PRINTING INKS BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 US disclosed
US-4081492-A POLYEPOXIDE BINDERS BAYER AKTIENGESELLSCHAFT (DT) 1978-03-28 US disclosed
US-4014771-A POLYEPOXIDES, BINDERS FOR PRINTING INKS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed