SCHEMBL19786306

SCHEMBL19786306

BN1CCCC(Cc2ccc(CC3CCCCN3B)cc2)C1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
CARM1 Q86X55 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
CCR3 P51677 2/20 0.32
BCHE P06276 1/20 0.32
ADRA1D P25100 3/20 0.32
ADRA1A P35348 3/20 0.32
ADRA1B P35368 3/20 0.32
HSD11B1 P28845 1/20 0.32
CHI3L1 P36222 1/20 0.32
SLC18A3 Q16572 1/20 0.31
P4HB P07237 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21732238 0.84 ALDH1A1 (0.38) LTA4HHRH3ADRA1DADRA1AADRA1B
SCHEMBL8273684 0.75 CHI3L1 (0.46) HRH3CHI3L1
SCHEMBL19786260 0.73
SCHEMBL19786261 0.71
SCHEMBL19786263 0.69
SCHEMBL12090378 0.63 CARM1 (0.48) HRH3CARM1PRMT6ADRA1DADRA1A
SCHEMBL10392609 0.63 CARM1 (0.58) CARM1PRMT6CCR3SLC18A3
SCHEMBL21216506 0.62 CYP2D6 (0.47) CARM1PRMT6CCR3
SCHEMBL21216508 0.62 LSS (0.55) CARM1PRMT6
SCHEMBL12090432 0.62 CYP2D6 (0.47) CARM1PRMT6CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10787562-B2 Silane-mediated enhancement of rubber storage stability TRINSEO EUROPE GMBH (CH) 2020-09-29 US disclosed
US-20200055881-A1 MULTIVINYLAMINOSILANES AS BRANCHING AGENTS FOR FUNCTIONALIZED ELASTOMERIC POLYMERS TRINSEO EUROPE GMBH (CH) 2020-02-20 US disclosed
US-10344147-B2 Functionalized polymer blend for a tire TRINSEO EUROPE GMBH (CH) 2019-07-09 US disclosed
US-20190169406-A1 SILANE-MEDIATED ENHANCEMENT OF RUBBER STORAGE STABILITY TRINSEO EUROPE GMBH (CH) 2019-06-06 US disclosed
US-20180037059-A1 A Polymer Blend for a Tire TRINSEO EUROPE GMBH (CH) 2018-02-08 US disclosed
US-20180016424-A1 Functionalized Polymer Blend for a Tire TRINSEO EUROPE GMBH (CH) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200055881-A1 MULTIVINYLAMINOSILANES AS BRANCHING AGENTS FOR FUNCTIONALIZED ELASTOMERIC POLYMERS PRUNE1, GNE, TERB1 LTA4H 1141/4885HRH3 1994/4885CARM1 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.