Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878521 | 0.92 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL23394602 | 0.92 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL13786400 | 0.90 | LMNA (0.52) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL13447791 | 0.89 | LMNA (0.51) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL15592313 | 0.89 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL13117380 | 0.89 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL12248448 | 0.89 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL13447797 | 0.89 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL14878523 | 0.89 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 | |
| SCHEMBL24997212 | 0.89 | LMNA (0.50) | LMNAKMT2APOLBCYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013999-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM CHEMICALS LLC (US) | 2018-01-18 | — | — | WO | disclosed |