SCHEMBL1978695

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17571121	0.89	HSPB1 (0.59)	KEAP1HSPB1ALDH1A1MAPTNPSR1
	SCHEMBL1980920	0.88	HSPB1 (0.55)	HSPB1ALDH1A1MAPTNPSR1POLB
	SCHEMBL1979539	0.84	HSPB1 (0.55)	HSPB1ALDH1A1MAPTNPSR1MEN1
	SCHEMBL6795644	0.81	HSPB1 (0.56)	HSPB1ALDH1A1MAPTNPSR1POLB
	SCHEMBL25200788	0.80	HSPB1 (0.59)	HSPB1ALDH1A1MAPTPOLBMEN1
	SCHEMBL6179891	0.78	HSPB1 (0.54)	HSPB1ALDH1A1MAPTNPSR1POLB
	SCHEMBL23160879	0.78	HSPB1 (0.51)	HSPB1ALDH1A1MAPTNPSR1POLB
	SCHEMBL27449389	0.78	HSPB1 (0.70)	HSPB1ALDH1A1MAPTNPSR1POLB
	SCHEMBL1979596	0.78	HSPB1 (0.53)	HSPB1ALDH1A1TP53MAPTPOLB
	SCHEMBL1980276	0.78	HSPB1 (0.56)	HSPB1ALDH1A1MAPTNPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.