SCHEMBL25200788

SCHEMBL25200788

COc1ccccc1Oc1ccc([N+](=O)[O-])cn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 2/20 0.59
MAPT P10636 11/20 0.58
PKM P14618 1/20 0.58
SMN1; SMN2 Q16637 9/20 0.57
LMNA P02545 6/20 0.57
HTT P42858 4/20 0.57
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
PABPC1 P11940 2/20 0.54
BLM P54132 1/20 0.54
RGS12 O14924 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
POLB P06746 1/20 0.53
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 2/20 0.52
APOBEC3A P31941 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52
PIN1 Q13526 1/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10983574 0.87 HSPB1 (0.55) HSPB1MAPTPKMSMN1; SMN2LMNA
SCHEMBL1980920 0.87 HSPB1 (0.55) HSPB1MAPTPKMSMN1; SMN2LMNA
SCHEMBL17571121 0.85 HSPB1 (0.59) HSPB1MAPTPKMSMN1; SMN2LMNA
SCHEMBL11133456 0.84 HSPB1 (0.58) HSPB1MAPTPKMSMN1; SMN2LMNA
SCHEMBL1980276 0.83 HSPB1 (0.56) HSPB1MAPTPKMSMN1; SMN2LMNA
SCHEMBL4715000 0.82 MAPT (0.57) HSPB1MAPTSMN1; SMN2LMNAHTT
SCHEMBL12469258 0.82 MAPT (0.50) HSPB1MAPTPKMSMN1; SMN2LMNA
SCHEMBL4715002 0.82 MAPT (0.57) HSPB1MAPTSMN1; SMN2LMNAHTT
SCHEMBL16792542 0.82 HSPB1 (0.75) HSPB1MAPTPKMSMN1; SMN2LMNA
SCHEMBL25184221 0.82 KMT2A (0.60) HSPB1MAPTPKMSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4097111-B9 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2025-10-29 EP disclosed
US-12415815-B2 Pyrido[2,3-e]oxazine derivatives as agricultural chemicals GLOBACHEM NV (BE) 2025-09-16 US disclosed
EP-4097111-B1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2025-07-23 EP disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS PNPO, HPD, PDXK HSPB1 2806/4885MAPT 553/4885PKM 952/4885
US-12415815-B2 Pyrido[2,3-e]oxazine derivatives as agricultural chemicals PNPO, HPD, PDXK HSPB1 2806/4885MAPT 553/4885PKM 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.