Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742756 | 1.00 | FOLH1 (0.42) | FOLH1PRMT1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL19360008 | 0.83 | PRMT1 (0.49) | FOLH1PRMT1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL15275337 | 0.81 | EPHX1 (0.49) | FOLH1PRMT1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL2742770 | 0.81 | FOLH1 (0.48) | FOLH1PRMT1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL12304382 | 0.81 | FOLH1 (0.63) | FOLH1EPHX2RIMKLANAALAD2 | |
| SCHEMBL15828219 | 0.80 | GABRP (0.42) | FOLH1PRMT1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL12118207 | 0.79 | PRMT1 (0.45) | FOLH1PRMT1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL24253219 | 0.78 | FOLH1 (0.42) | FOLH1ANPEPENPEPRIMKLANAALAD2 | |
| SCHEMBL15762839 | 0.76 | PRMT1 (0.44) | FOLH1PRMT1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL12553859 | 0.73 | MAPK1 (0.56) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872913-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER INC. (US) | 2018-01-23 | — | — | US | disclosed |