SCHEMBL17615103

SCHEMBL17615103

CCC[C@H](NC(=O)NCCC(C)(C)C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FPR2 P25090 1/20 0.44
▸ FOLH1 Q04609 7/20 0.43
▸ RIMKLA Q8IXN7 1/20 0.41
▸ NAALAD2 Q9Y3Q0 1/20 0.41
▸ GRN P28799 2/20 0.40
▸ SORT1 Q99523 2/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ MAPT P10636 1/20 0.39
▸ KDM4C Q9H3R0 1/20 0.38
▸ CTSS P25774 1/20 0.38
▸ CTSK P43235 1/20 0.38
▸ CCKBR P32239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10089708 0.86 FOLH1 (0.61) FOLH1RIMKLANAALAD2CCKBR
SCHEMBL18538622 0.80 FPR2 (0.47) FPR2FOLH1RIMKLANAALAD2SMN1; SMN2
SCHEMBL18538620 0.79 FOLH1 (0.48) FPR2FOLH1SMN1; SMN2
SCHEMBL18253627 0.77 FOLH1 (0.49) FPR2FOLH1RIMKLANAALAD2SMN1; SMN2
SCHEMBL19788064 0.77 FOLH1 (0.49) FPR2FOLH1RIMKLANAALAD2SMN1; SMN2
SCHEMBL10089711 0.73 FOLH1 (0.67) FOLH1RIMKLANAALAD2
SCHEMBL13559294 0.73 FOLH1 (0.67) FOLH1RIMKLANAALAD2
SCHEMBL19703744 0.73 EPHX1 (0.53) SMN1; SMN2KDM4CCCKBR
SCHEMBL26830774 0.73 FOLH1 (0.57) FOLH1
SCHEMBL23874511 0.73 EPHX1 (0.54) SMN1; SMN2KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556167-B2 TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs) YALE UNIVERSITY (US) 2017-01-31 — — US disclosed
US-20160082112-A1 SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160082112-A1 SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER CD47, FCGR1A, FCGR2A FPR2 410/4885FOLH1 12/4885RIMKLA 1667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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