Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580764 | 1.00 | CYP3A4 (0.47) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL10352998 | 0.95 | CNR1 (0.51) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL10352996 | 0.95 | CNR1 (0.51) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL9000683 | 0.93 | CYP3A4 (0.45) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL8749007 | 0.90 | CNR1 (0.53) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL8749004 | 0.90 | CNR1 (0.53) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL5690828 | 0.90 | CNR1 (0.53) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL8748877 | 0.90 | CNR1 (0.53) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL8748936 | 0.86 | CNR1 (0.46) | CYP3A4TSHRTDP1ATMCNR1 | |
| SCHEMBL8748940 | 0.86 | CNR1 (0.46) | CYP3A4TSHRTDP1ATMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150094206-A1 | Biocide Compositions Comprising Derivatives Of Pyroglutamic Acid | COGNIS IP MAN GMBH (DE) | 2015-04-02 | — | — | US | claimed |
| US-20130102467-A1 | Biocide Compositions Comprising Derivatives of Pyroglutamic Acid | COGNIS IP MANAGEMENT GMBH (DE) | 2013-04-25 | — | — | US | claimed |
| WO-2011072811-A2 | BIOCIDE COMPOSITIONS COMPRISING DERIVATIVES OF PYROGLUTAMIC ACID | COGNIS IP MANAGEMENT GMBH (DE) | 2011-06-23 | — | — | WO | claimed |
| EP-2335480-A1 | Biocide compositions comprising derivatives of pyroglutamic acid | Cognis IP Management GmbH (DE) | 2011-06-22 | — | — | EP | claimed |
| EP-0342056-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-08-17 | — | — | EP | claimed |
| EP-0277428-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-03-23 | — | — | EP | claimed |
| EP-0342055-B1 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1994-01-12 | — | — | EP | claimed |
| EP-0342054-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1993-11-03 | — | — | EP | claimed |
| EP-0342056-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342054-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342055-A2 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0277428-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1988-08-10 | — | — | EP | claimed |
| EP-2775839-B1 | METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | UNIV CALIFORNIA (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20230265268-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | POLYMAX THERMOPLASTIC ELASTOMERS, LLC | 2023-08-24 | — | — | US | disclosed |
| US-20150094206-A1 | Biocide Compositions Comprising Derivatives Of Pyroglutamic Acid | COGNIS IP MAN GMBH (DE) | 2015-04-02 | — | — | US | disclosed |
| US-8927460-B2 | Biocide compositions comprising derivatives of pyroglutamic acid | COGNIS IP MANAGEMENT GMBH (DE) | 2015-01-06 | — | — | US | disclosed |
| US-4832946-A | CELL CULTURE FOR HAIR GROWTH | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY | 1989-05-23 | — | — | US | disclosed |
| EP-0295092-A2 | Skin treatment composition | UNILEVER PLC (GB) | 1988-12-14 | — | — | EP | disclosed |
| EP-0277428-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| EP-0272920-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1988-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102467-A1 | Biocide Compositions Comprising Derivatives of Pyroglutamic Acid | GLUL, GLO1, PGD | CYP3A4 931/4885TSHR 4785/4885TDP1 2615/4885 |
| US-20150094206-A1 | Biocide Compositions Comprising Derivatives Of Pyroglutamic Acid | GLUL, GLO1, PGD | CYP3A4 931/4885TSHR 4785/4885TDP1 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.