Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 19/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72985 | 0.88 | PDE4D (0.59) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17207630 | 0.83 | CNR2 (0.49) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5793577 | 0.81 | PDE4B (0.55) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29733437 | 0.81 | CNR2 (0.48) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1433277 | 0.81 | CNR2 (0.48) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1978878 | 0.80 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL71158 | 0.78 | TRPC6 (0.48) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL88281 | 0.77 | TRPC6 (0.49) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL18708221 | 0.77 | TRPC6 (0.49) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL3633786 | 0.76 | TRPC6 (0.54) | PDE4APDE4BPDE4CPDE4DCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935219-A1 | METHOD OF PREPARATION OF CRYSTAL FORMS OF 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDOPYRIDYN-4-yl)-5-METHOXYPYRIDINE-2-CARBOXAMIDE AND CRISTAL FORMS THEREOF | SANOFI (FR) | 2015-10-28 | — | — | EP | claimed |
| WO-2014083107-A1 | METHOD OF PREPARATION OF CRYSTAL FORMS OF 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDOPYRIDYN-4-yl)-5-METHOXYPYRIDINE-2-CARBOXAMIDE AND CRISTAL FORMS THEREOF | SANOFI (FR) | 2014-06-05 | — | — | WO | claimed |
| EP-4281065-A1 | ENHANCEMENT OF CAMP SIGNALING AS A COMBINATION DRUG STRATEGY FOR THE TREATMENT OF DEPRESSION AND RELATED CONDITIONS | Alto Neuroscience, Inc. (US) | 2023-11-29 | — | — | EP | disclosed |
| EP-2935219-A1 | METHOD OF PREPARATION OF CRYSTAL FORMS OF 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDOPYRIDYN-4-yl)-5-METHOXYPYRIDINE-2-CARBOXAMIDE AND CRISTAL FORMS THEREOF | SANOFI (FR) | 2015-10-28 | — | — | EP | disclosed |
| EP-2935239-A1 | PROCESS FOR PREPARING 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDO-4-PYRIDYL)-5-METHOXYPYRIDINE-2-CARBOXAMIDE | SANOFI (FR) | 2015-10-28 | — | — | EP | disclosed |
| CN-104955820-A | Process for preparing 4-(cyclopropylmethoxy)-n-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridine-2-carboxamide | SAI NUOFEI | 2015-09-30 | — | — | CN | disclosed |
| WO-2014083107-A1 | METHOD OF PREPARATION OF CRYSTAL FORMS OF 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDOPYRIDYN-4-yl)-5-METHOXYPYRIDINE-2-CARBOXAMIDE AND CRISTAL FORMS THEREOF | SANOFI (FR) | 2014-06-05 | — | — | WO | disclosed |
| WO-2014083106-A1 | PROCESS FOR PREPARING 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDO-4-PYRIDYL)-5-METHOXYPYRIDINE-2-CARBOXAMIDE | SANOFI (FR) | 2014-06-05 | — | — | WO | disclosed |
| EP-2146714-B1 | USE OF 4-CYCLOPROPYLMETHOXY-<I>N</I>-(3,5-DICHLORO-1-OXIDOPYRIDIN-4-YL)-5-(METHOXY)PYRIDINE-2-CARBOXAMIDE FOR THE TREATMENT OF MOTOR DISORDERS RELATED TO PARKINSON'S DISEASE | SANOFI AVENTIS (FR) | 2011-06-22 | — | — | EP | disclosed |