SCHEMBL19789513

SCHEMBL19789513

COc1cccc(CCNC(=O)CCc2ccc(O)c(OC)c2)c1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
ALDH1A1 P00352 1/20 0.60
POLB P06746 1/20 0.60
ALOX5 P09917 1/20 0.57
OR51E2 Q9H255 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21328352 0.91 CA1 (0.78) CA1CA2ALDH1A1POLB
SCHEMBL4024309 0.91 KMT2A (0.80) MEN1KMT2AALDH1A1POLB
SCHEMBL1915903 0.90 MEN1 (0.70) MEN1KMT2ACA1CA2ALOX5
SCHEMBL2378930 0.87 MEN1 (0.65) MEN1KMT2AALOX5OR51E2
SCHEMBL25512198 0.85 ALOX5 (0.80) ALDH1A1POLBALOX5OR51E2
SCHEMBL2376785 0.85 MEN1 (0.67) MEN1KMT2AALDH1A1ALOX5OR51E2
SCHEMBL14432087 0.84 KMT2A (0.66) MEN1KMT2AALDH1A1ALOX5OR51E2
SCHEMBL9921169 0.82 MEN1 (0.60) MEN1KMT2AALOX5OR51E2
SCHEMBL11948294 0.81 CA1 (0.74) MEN1KMT2ACA1CA2ALDH1A1
SCHEMBL24528927 0.81 MTNR1A (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2347754-B1 Oral and tooth care and cleaning agents with alkylpyridinium salts I HENKEL AG & CO KGAA (DE) 2018-01-24 EP disclosed