Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961872 | 0.93 | HTT (0.48) | KMT2ATDP1POLBAPEX1HTT | |
| SCHEMBL14907479 | 0.92 | LMNA (0.41) | KMT2ATDP1POLBAPEX1HTT | |
| SCHEMBL19789553 | 0.91 | POLB (0.52) | KMT2ATDP1POLBAPEX1HTT | |
| SCHEMBL16133504 | 0.90 | NPC1 (0.51) | KMT2ATDP1POLBAPEX1HTT | |
| SCHEMBL803172 | 0.86 | TDP1 (0.56) | KMT2ATDP1POLBAPEX1HTT | |
| SCHEMBL11986168 | 0.85 | MAPT (0.38) | KMT2ATDP1POLBMAPTL3MBTL1 | |
| SCHEMBL26037671 | 0.84 | KMT2A (0.43) | KMT2ATDP1MAPTL3MBTL1GAA | |
| SCHEMBL21091143 | 0.84 | POLB (0.52) | KMT2ATDP1POLBAPEX1HTT | |
| SCHEMBL14088561 | 0.84 | POLB (0.41) | KMT2ATDP1POLBAPEX1HTT | |
| SCHEMBL18869268 | 0.84 | TDP1 (0.54) | KMT2ATDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |