Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.38 |
| ▸ | CCR2 | P41597 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789665 | 0.89 | DDR1 (0.35) | DDR1CCR2CA1CA2CA9 | |
| SCHEMBL13619881 | 0.85 | CCR2 (0.37) | CCR2 | |
| SCHEMBL19789692 | 0.85 | CCR2 (0.37) | CCR2 | |
| SCHEMBL19789827 | 0.78 | SLC6A2 (0.32) | DDR1CCR2 | |
| SCHEMBL19789821 | 0.74 | CCR2 (0.39) | CCR2 | |
| SCHEMBL19789882 | 0.70 | CCR2 (0.37) | CCR2 | |
| SCHEMBL19789756 | 0.70 | CCR2 (0.37) | CCR2 | |
| SCHEMBL19789753 | 0.65 | MAOA (0.38) | — | |
| SCHEMBL13620313 | 0.65 | MAOA (0.38) | — | |
| SCHEMBL19789740 | 0.65 | MAPK14 (0.36) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |