Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620313 | 0.84 | MAOA (0.38) | TSHR | |
| SCHEMBL19789753 | 0.84 | MAOA (0.38) | TSHR | |
| SCHEMBL19789740 | 0.80 | MAPK14 (0.36) | DDR1 | |
| SCHEMBL19789790 | 0.78 | — | — | |
| SCHEMBL19789818 | 0.78 | DDR1 (0.38) | CCR2DDR1 | |
| SCHEMBL19789877 | 0.72 | LMNA (0.35) | TSHR | |
| SCHEMBL19789770 | 0.69 | CYP19A1 (0.38) | TSHR | |
| SCHEMBL19789665 | 0.69 | DDR1 (0.35) | CCR2DDR1 | |
| SCHEMBL19789724 | 0.68 | MEN1 (0.39) | TP53TSHR | |
| SCHEMBL13620463 | 0.68 | MEN1 (0.39) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |