Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196386 | 0.73 | CYP4F2 (0.32) | — | |
| SCHEMBL12221619 | 0.73 | — | — | |
| SCHEMBL20885267 | 0.73 | CYP2C19 (0.34) | CYP2C19 | |
| SCHEMBL1781887 | 0.71 | TDP1 (0.48) | FFAR1CPT2TDP1FDPSCES1 | |
| SCHEMBL14296502 | 0.71 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL1783727 | 0.70 | CES1 (0.39) | FFAR1CPT2TDP1CES1CES2 | |
| SCHEMBL20078059 | 0.69 | CYP2C19 (0.38) | FFAR1CPT2TDP1CES2CYP2C19 | |
| SCHEMBL12710486 | 0.69 | — | — | |
| SCHEMBL14280360 | 0.68 | ACLY (0.31) | ALDH1A1CYP2C19 | |
| SCHEMBL5611289 | 0.68 | TDP1 (0.50) | FFAR1CPT2TDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |