Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742957 | 0.79 | PTGER4 (0.54) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11314258 | 0.77 | PTGER4 (0.53) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21137032 | 0.73 | CYP3A4 (0.34) | ALDH1A1MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL7734442 | 0.72 | NCF1 (0.56) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4792453 | 0.72 | BACE1 (0.51) | KDM4EHPGDHSD17B10 | |
| SCHEMBL18394468 | 0.70 | PTGER4 (0.46) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20837291 | 0.70 | NCF1 (0.44) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7965576 | 0.70 | PTGER4 (0.46) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7745287 | 0.69 | PTGER4 (0.51) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1421397 | 0.68 | PTGER4 (0.47) | PTGER4NCF1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799431-B1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2018-01-24 | — | — | EP | disclosed |