Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18013010 | 0.80 | PBRM1 (1.00) | PBRM1ARCYP19A1MAOAMAOB | |
| SCHEMBL31015961 | 0.80 | PBRM1 (1.00) | PBRM1ARCYP19A1MAOAMAOB | |
| SCHEMBL11111435 | 0.79 | RORC (0.42) | PBRM1ARKMT2ACYP3A4HIF1A | |
| SCHEMBL15537195 | 0.78 | PBRM1 (0.61) | PBRM1ARCYP19A1MAOAMAOB | |
| SCHEMBL6836628 | 0.78 | MAOB (0.56) | ARCYP19A1MAOBCYP3A4ABCB1 | |
| SCHEMBL12303262 | 0.78 | PNMT (0.44) | PBRM1ARMAPTLMNATDP1 | |
| SCHEMBL19188361 | 0.77 | CNR1 (0.52) | PBRM1ARKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL11556142 | 0.76 | PTGS2 (0.49) | PBRM1ARKMT2AMEN1CYP2C9 | |
| SCHEMBL19271787 | 0.76 | PBRM1 (0.66) | PBRM1ARCYP19A1MAOAMAOB | |
| SCHEMBL15537413 | 0.76 | PBRM1 (0.66) | PBRM1ARCYP19A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199530-A1 | BENZOFURAN ANALOGUE AS NS4B INHIBITOR | Changzhou Yinsheng Pharmaceutical Co., Ltd. (CN) | 2017-08-02 | — | — | EP | disclosed |
| WO-2011072064-A1 | S PIRO [CHROMAN - 4, 4 ' - IMIDAZOL] ONES AS BETA - SECRETASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | WO | disclosed |