Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18536403 | 0.79 | MEN1 (0.42) | NAMPT | |
| SCHEMBL12906743 | 0.75 | CYP2C9 (0.38) | NAMPT | |
| SCHEMBL15220576 | 0.71 | TGM2 (0.42) | NAMPT | |
| SCHEMBL14000671 | 0.71 | ERCC1 (0.41) | NAMPT | |
| SCHEMBL7877576 | 0.69 | — | — | |
| SCHEMBL14394123 | 0.69 | HDAC1 (0.34) | NAMPT | |
| SCHEMBL25885492 | 0.67 | HSD11B1 (0.44) | — | |
| SCHEMBL25015336 | 0.67 | NAMPT (0.31) | NAMPT | |
| SCHEMBL13494196 | 0.67 | NR4A2 (0.31) | NAMPT | |
| SCHEMBL25785477 | 0.66 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726454-B1 | PROCESS | BIAL-PORTELA & CA S A (PT) | 2018-01-24 | — | — | EP | disclosed |