SCHEMBL19791252

SCHEMBL19791252

C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 14/20 0.55
▸ PRMT1 Q99873 1/20 0.52
▸ NPBWR1 P48145 1/20 0.51
▸ IL23R Q5VWK5 2/20 0.50
▸ RXFP1 Q9HBX9 1/20 0.49
▸ CXCR4 P61073 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19791177 0.95 KISS1R (0.55) KISS1RPRMT1NPBWR1IL23RRXFP1
SCHEMBL19791186 0.95 KISS1R (0.55) KISS1RPRMT1NPBWR1IL23RRXFP1
SCHEMBL31345040 0.94 KISS1R (0.56) KISS1RPRMT1NPBWR1
SCHEMBL19791170 0.94 IL23R (0.56) KISS1RPRMT1IL23RRXFP1
SCHEMBL19791161 0.94 IL23R (0.56) KISS1RIL23RRXFP1
SCHEMBL30641908 0.90 NPY1R (0.50) KISS1R
SCHEMBL30641912 0.90 NPY1R (0.50) KISS1R
SCHEMBL30641907 0.90 NPY1R (0.50) KISS1R
SCHEMBL30632098 0.90 ACE (0.53) PRMT1
SCHEMBL31232961 0.90 IL23R (0.51) KISS1RNPBWR1IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148474-A1 PEPTIDE DERIVATIVE FOR REGULATING THYMIC STROMAL LYMPHOID PROTEIN-MEDIATED SIGNALING AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ALLERGY AND ASTHMA DISEASES COMPRISING SAME KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2018-05-31 — — US disclosed
EP-3272765-A1 PEPTIDE DERIVATIVE FOR REGULATING THYMIC STROMAL LYMPHOID PROTEIN-MEDIATED SIGNALING AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ALLERGY AND ASTHMA DISEASES COMPRISING SAME Korea University Research and Business Foundation, Sejong Campus (KR) 2018-01-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180148474-A1 PEPTIDE DERIVATIVE FOR REGULATING THYMIC STROMAL LYMPHOID PROTEIN-MEDIATED SIGNALING AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ALLERGY AND ASTHMA DISEASES COMPRISING SAME TSLP, CXCL12, CCL11 KISS1R 3485/4885PRMT1 887/4885NPBWR1 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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