Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28244471 | 0.83 | KIF11 (0.38) | KIF11KDM4ENPC1NFKB1RAB9A | |
| SCHEMBL28540008 | 0.81 | TRPV1 (0.41) | KIF11MAPK1KDM4EALDH1A1 | |
| SCHEMBL28436016 | 0.81 | KIF11 (0.54) | KIF11NPC1ALDH1A1RAB9ADGAT1 | |
| SCHEMBL28241016 | 0.80 | ESR1 (0.50) | KIF11ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL27699321 | 0.77 | PTPN5 (0.44) | KIF11 | |
| SCHEMBL12675678 | 0.75 | KIF11 (1.00) | KIF11ESR1ESR2MAPK1MAP2K4 | |
| SCHEMBL678508 | 0.75 | KIF11 (1.00) | KIF11ESR1ESR2MAPK1MAP2K4 | |
| SCHEMBL29275313 | 0.73 | KIF11 (0.64) | KIF11ALDH1A1DGAT1KCNH2 | |
| SCHEMBL57109 | 0.72 | KIF11 (0.84) | KIF11ESR1ESR2KDM4ENPC1 | |
| SCHEMBL21268187 | 0.71 | KIF11 (0.43) | KIF11ESR1ESR2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509978-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E.I. Du Pont De Nemours And Company (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |