Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967710 | 0.86 | FFAR1 (0.44) | FFAR1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL4319595 | 0.85 | ATM (0.57) | NPC1RAB9ACASP3SENP7POLB | |
| Hydrochloric Acid SCHEMBL21391937 | 0.85 | FFAR1 (0.43) | FFAR1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL17967116 | 0.84 | FFAR1 (0.52) | FFAR1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL19801239 | 0.82 | FFAR1 (0.44) | FFAR1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL20901751 | 0.82 | FFAR1 (0.44) | FFAR1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL8840334 | 0.77 | CSNK2A2 (0.56) | NPC1RAB9AHDAC1LMNASMN1; SMN2 | |
| SCHEMBL17967711 | 0.73 | ATM (0.69) | POLBLMNAALDH1A1GLSATM | |
| Hydrochloric Acid SCHEMBL21391938 | 0.72 | ATM (0.67) | POLBLMNAALDH1A1GLSATM | |
| SCHEMBL17967183 | 0.71 | FFAR1 (0.48) | FFAR1NPC1RAB9ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022742-A1 | AUTOTAXIN INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022742-A1 | AUTOTAXIN INHIBITORS | ENPP2, RNASE1, ATXN10 | FFAR1 4417/4885NPC1 4099/4885RAB9A 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.