Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984297 | 0.87 | RAB9A (0.46) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL1978197 | 0.81 | MAPT (0.43) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL1979585 | 0.81 | MAPT (0.43) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL17350072 | 0.77 | KMT2A (0.45) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL13832464 | 0.76 | LTA4H (0.51) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL1978975 | 0.76 | RAB9A (0.48) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL1980293 | 0.76 | AR (0.41) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL13268415 | 0.76 | LTA4H (0.48) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL21980932 | 0.76 | LTA4H (0.48) | RAB9AGAAALDH1A1MAPTKMT2A | |
| SCHEMBL13720846 | 0.76 | GAA (0.42) | RAB9AGAAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509961-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | Autifony Therapeutics Limited (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069951-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |