Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978197 | 0.78 | MAPT (0.43) | ALDH1A1MAPTGFERPKMMEN1 | |
| SCHEMBL1979585 | 0.78 | MAPT (0.43) | ALDH1A1MAPTGFERPKMMEN1 | |
| SCHEMBL13721071 | 0.77 | MAPT (0.37) | ARALDH1A1MAPTGFERPKM | |
| SCHEMBL19400305 | 0.77 | MAPT (0.41) | ARALDH1A1MAPTGFERPKM | |
| SCHEMBL1979333 | 0.76 | RAB9A (0.43) | ALDH1A1MAPTGFERPKMMEN1 | |
| SCHEMBL13828839 | 0.76 | CTSS (0.39) | ARALDH1A1MAPTGFERPKM | |
| SCHEMBL13721062 | 0.76 | AR (0.38) | ARALDH1A1MAPTPKMHRH3 | |
| SCHEMBL17350073 | 0.75 | AR (0.37) | ARALDH1A1MAPTGFERPKM | |
| SCHEMBL1978918 | 0.73 | PTGDR2 (0.40) | ARALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17354619 | 0.73 | AR (0.40) | ARHRH3RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509961-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | Autifony Therapeutics Limited (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069951-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |