Sugi Predict

Sugi Predict / Compounds / SCHEMBL19793344

SCHEMBL19793344

SCHEMBL19793344

COc1ccc2cc(C)oc(=O)c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 10/20 0.54
▸ ALDH1A1 P00352 10/20 0.54
▸ MAPT P10636 7/20 0.54
▸ NPC1 O15118 2/20 0.54
▸ RAB9A P51151 2/20 0.54
▸ POLB P06746 2/20 0.54
▸ STAT1 P42224 1/20 0.54
▸ HPGD P15428 8/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ CASP3 P42574 2/20 0.50
▸ SENP7 Q9BQF6 2/20 0.50
▸ SENP8 Q96LD8 1/20 0.50
▸ SENP6 Q9GZR1 1/20 0.50
▸ ESR2 Q92731 2/20 0.49
▸ HSD17B10 Q99714 5/20 0.49
▸ CA12 O43570 2/20 0.49
▸ CA3 P07451 2/20 0.49
▸ CA4 P22748 2/20 0.49
▸ CA6 P23280 2/20 0.49
▸ CA7 P43166 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14158289 0.86 ALDH1A1 (0.54) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL19793345 0.78 ELANE (0.53) KDM4EALDH1A1MAPTPOLBCA9
SCHEMBL19793674 0.78 ALDH1A1 (0.49) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL17114050 0.76 ALDH1A1 (0.56) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL26767762 0.76 KDM4E (0.79) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL29853560 0.76 KDM4E (0.79) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL11847702 0.75 ALDH1A1 (0.47) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL17114055 0.75 KDM4E (0.58) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL9108334 0.74 LCK (0.50) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL719714 0.74 ALDH1A1 (0.59) KDM4EALDH1A1NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428273-B2 Liquid crystal compound having benzopyran skeleton, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2019-10-01 — — US disclosed
US-20180022998-A1 LIQUID CRYSTAL COMPOUND HAVING BENZOPYRAN SKELETON, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-25 — — US disclosed
US-20180022998-A1 LIQUID CRYSTAL COMPOUND HAVING BENZOPYRAN SKELETON, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428273-B2 Liquid crystal compound having benzopyran skeleton, liquid crystal composition, and liquid crystal display device PIEZO1, PYCARD, NLRP1 KDM4E 2394/4885ALDH1A1 2282/4885MAPT 161/4885
US-20180022998-A1 LIQUID CRYSTAL COMPOUND HAVING BENZOPYRAN SKELETON, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE PIEZO1, NLRP1, PYCARD KDM4E 2257/4885ALDH1A1 2304/4885MAPT 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.