SCHEMBL19794326

SCHEMBL19794326

CC1(C)OB(c2ccc(-c3ccc4c(c3)C3CCC4CC3)nc2)OC1(C)C

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.49
LIPG Q9Y5X9 10/20 0.39
LPL P06858 9/20 0.39
PDGFRB P09619 1/20 0.34
KDR P35968 1/20 0.34
USP30 Q70CQ3 1/20 0.34
SNCA P37840 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.32
HIF1A Q16665 1/20 0.31
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19295082 0.95 DGAT1 (0.47) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL19933760 0.89 DGAT1 (0.47) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL19794327 0.89 DGAT1 (0.47) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL19295084 0.85 DGAT1 (0.47) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL21662364 0.85 DGAT1 (0.43) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL23956048 0.82 DGAT1 (0.44) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL23956047 0.81 DGAT1 (0.42) DGAT1LIPGLPL
SCHEMBL21125910 0.81 DGAT1 (0.57) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL21125909 0.81 DGAT1 (0.67) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL21662278 0.81 DGAT1 (0.41) DGAT1LIPGLPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145828-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-10-12 US disclosed
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 US disclosed
EP-3507294-B1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-24 EP disclosed
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices MERCK PATENT GMBH 2021-01-12 US disclosed
US-20190252628-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-15 US disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-07-04 US disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES PARN, PUF60, PARG DGAT1 2586/4885LIPG 4374/4885LPL 4558/4885
US-11145828-B2 Metal complexes AP1M1, AP2M1, AP3M1 DGAT1 2072/4885LIPG 3552/4885LPL 3726/4885
US-20190252628-A1 METAL COMPLEXES AP1M1, AP2M1, AP3M1 DGAT1 2072/4885LIPG 3552/4885LPL 3726/4885
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC DGAT1 1835/4885LIPG 4459/4885LPL 4682/4885
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices PARN, PUF60, PARG DGAT1 2586/4885LIPG 4374/4885LPL 4558/4885
US-20180026209-A1 Metal Complexes AP3M1, AP2M1, SOD1 DGAT1 1328/4885LIPG 3693/4885LPL 3416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.