Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.37 |
| ▸ | LPL | P06858 | 8/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19794327 | 1.00 | DGAT1 (0.47) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL19295082 | 0.89 | DGAT1 (0.47) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL23956047 | 0.89 | DGAT1 (0.42) | DGAT1LIPGLPLKDM1A | |
| SCHEMBL19794326 | 0.89 | DGAT1 (0.49) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL21125417 | 0.88 | DGAT1 (0.41) | DGAT1LIPGLPL | |
| SCHEMBL21662278 | 0.88 | DGAT1 (0.41) | DGAT1LIPGLPL | |
| SCHEMBL21125836 | 0.85 | DGAT1 (0.39) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL21662364 | 0.84 | DGAT1 (0.43) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL21398051 | 0.81 | DGAT1 (0.41) | DGAT1LIPGLPLHIF1A | |
| SCHEMBL16905132 | 0.81 | LIPG (0.40) | LIPGLPLIRAK4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601257-B1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2018041769-A1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-03-08 | — | — | WO | disclosed |