SCHEMBL19794402

SCHEMBL19794402

Brc1ccc(-n2nc3ccccc3n2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.67
HPGD P15428 3/20 0.67
HTT P42858 1/20 0.57
NPC1 O15118 10/20 0.46
RAB9A P51151 10/20 0.46
ALDH1A1 P00352 6/20 0.46
MAPT P10636 5/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
STAT1 P42224 1/20 0.46
GABRA1 P14867 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRA6 Q16445 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
GAA P10253 2/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14281095 0.83 NPC1 (0.49) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL29394943 0.81 KDM4E (0.53) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL459011 0.80 KDM4E (1.00) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL8621203 0.79 KDM4E (0.63) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL19993879 0.77 KDM4E (0.67) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL1619956 0.77 KDM4E (0.67) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL5537671 0.77 KDM4E (0.67) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL8995917 0.77 KDM4E (0.67) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL2670040 0.77 KDM4E (0.67) KDM4EHPGDHTTNPC1RAB9A
SCHEMBL28395544 0.77 KDM4E (0.74) KDM4EHPGDHTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436971-A Di (4- (benzoxazol-2-yl) phenyl) methylamine derivative and preparation method thereof 陕西维世诺新材料有限公司 2022-05-06 CN claimed
US-12281248-B2 Organic light-emitting element using polycyclic aromatic derivative compound SFC CO., LTD. (KR) 2025-04-22 US disclosed
EP-3941159-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2025-04-16 EP disclosed
US-12219872-B2 Organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2025-02-04 US disclosed
CN-113424657-B Organic electroluminescent element 保土谷化学工业株式会社 2024-08-13 CN disclosed
US-20240260457-A1 ORGANIC EL DEVICE, AMINE COMPOUND HAVING BENZAZOLE RING STRUCTURE, AND METHOD IN WHICH SAID AMINE COMPOUND IS USED IN CAPPING LAYER OF ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2024-08-01 US disclosed
CN-113166641-B Organic light-emitting element using polycyclic aromatic derivative compound SFC株式会社 2024-06-04 CN disclosed
US-11980092-B2 Organic electroluminescence element HODOGAYA CHEMICAL CO., LTD. (JP) 2024-05-07 US disclosed
US-11974499-B2 Organic EL device, amine compound having benzazole ring structure, and method in which said amine compound is used in capping layer of organic EL device HODOGAYA CHEMICAL CO., LTD. (JP) 2024-04-30 US disclosed
EP-3432688-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-12-20 EP disclosed
EP-3740036-A1 ORGANIC EL ELEMENT, AMINE COMPOUND HAVING BENZOAZOLE RING STRUCTURE, AND METHOD IN WHICH SAID AMINE COMPOUND IS USED IN CAPPING LAYER OF ORGANIC EL ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2020-11-18 EP disclosed
US-20200328353-A1 Organic Electroluminescence Device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-10-15 US disclosed
CN-111567141-A Organic EL element, amine compound having benzoxazole ring structure, and method for using same in capping layer of organic EL element 保土谷化学工业株式会社 2020-08-21 CN disclosed
WO-2020137724-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2020-07-02 WO disclosed
CN-111100082-A Preparation method of 2-aryl benzotriazole compound 温州大学 2020-05-05 CN disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
EP-3432688-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2019-01-23 EP disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed
CN-1761787-A Oxidation system comprising macrocyclic metal complexes, method for the production and use thereof LANXESS B V (NL) 2006-04-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180026209-A1 Metal Complexes AP3M1, AP2M1, SOD1 KDM4E 3864/4885HPGD 4429/4885HTT 1827/4885
US-12281248-B2 Organic light-emitting element using polycyclic aromatic derivative compound TRPA1, TYR, ZKSCAN2 KDM4E 582/4885HPGD 3907/4885HTT 2112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.