Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | LDHA | P00338 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19794429 | 1.00 | HSD17B1 (0.43) | HSD17B1HSD17B2LDHAHPGDSBAZ2B | |
| SCHEMBL19794369 | 0.96 | HSD17B1 (0.43) | HSD17B1HSD17B2RARBRARGRXRA | |
| SCHEMBL18015605 | 0.93 | HSD17B1 (0.38) | HSD17B1HSD17B2LDHAHPGDSBAZ2B | |
| SCHEMBL21020849 | 0.93 | HSD17B1 (0.38) | HSD17B1HSD17B2LDHAHPGDSBAZ2B | |
| SCHEMBL19794463 | 0.93 | HSD17B1 (0.38) | HSD17B1HSD17B2LDHAHPGDSBAZ2B | |
| SCHEMBL19833588 | 0.93 | HSD17B1 (0.38) | HSD17B1HSD17B2LDHAHPGDSBAZ2B | |
| SCHEMBL21125840 | 0.90 | HSD17B1 (0.37) | HSD17B1HSD17B2RARBRARGRXRA | |
| SCHEMBL19834635 | 0.90 | HSD17B1 (0.38) | HSD17B1HSD17B2RARBRARGRXRA | |
| SCHEMBL18015499 | 0.88 | HSD17B1 (0.38) | HSD17B1HSD17B2RARBRARGRXRA | |
| SCHEMBL21398044 | 0.88 | HSD17B1 (0.39) | HSD17B1HSD17B2LDHAHPGDSBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487865-B1 | DINUCLEAR AND OLIGONUCLEAR METAL COMPLEXES CONTAINING TRIPODAL BIDENTATE PART LIGANDS AND THEIR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-11-23 | — | — | EP | disclosed |
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20190157578-A1 | DINUCLEAR AND OLIGONUCLEAR METAL COMPLEXES CONTAINING TRIPODAL BIDENTATE PART LIGANDS AND THEIR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-05-23 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | HSD17B1 4860/4885HSD17B2 4834/4885LDHA 2726/4885 |
| US-20190157578-A1 | DINUCLEAR AND OLIGONUCLEAR METAL COMPLEXES CONTAINING TRIPODAL BIDENTATE PART LIGANDS AND THEIR USE IN ELECTRONIC DEVICES | SSBP1, POLRMT, BICRA | HSD17B1 4744/4885HSD17B2 4759/4885LDHA 1047/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | HSD17B1 4527/4885HSD17B2 4245/4885LDHA 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.