Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015596 | 1.00 | LDHA (0.53) | LDHARAB9ANPC1SMN1; SMN2PDGFRB | |
| SCHEMBL23956296 | 0.97 | LDHA (0.50) | LDHARAB9ANPC1SMN1; SMN2PDGFRB | |
| SCHEMBL18015476 | 0.95 | LDHA (0.57) | LDHARAB9ANPC1SMN1; SMN2PDGFRB | |
| SCHEMBL18015292 | 0.90 | NPC1 (0.43) | LDHARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL23956250 | 0.89 | ENPP3 (0.46) | LDHARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19794359 | 0.88 | LDHA (0.48) | LDHARAB9ANPC1SMN1; SMN2PDGFRB | |
| SCHEMBL18015491 | 0.88 | LDHA (0.54) | LDHARAB9ANPC1SMN1; SMN2PDGFRB | |
| SCHEMBL23956256 | 0.88 | LDHA (0.54) | LDHARAB9ANPC1SMN1; SMN2PDGFRB | |
| SCHEMBL21202787 | 0.88 | LDHA (0.50) | LDHARAB9ANPC1SMN1; SMN2PDGFRB | |
| SCHEMBL21125949 | 0.88 | LDHA (0.54) | LDHARAB9ANPC1SMN1; SMN2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | LDHA 2726/4885RAB9A 2171/4885NPC1 4039/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | LDHA 1917/4885RAB9A 1433/4885NPC1 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.