SCHEMBL19794447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18015696	0.85	KDM4E (0.43)	NPC1CYP11B1CYP11B2IDO1TDO2
	SCHEMBL19933641	0.82	KDM4E (0.39)	CYP11B1CYP11B2IDO1TDO2PDGFRB
	SCHEMBL18015574	0.79	LDHA (0.52)	CYP11B1CYP11B2IDO1TDO2LDHA
	SCHEMBL19933578	0.79	LDHA (0.52)	CYP11B1CYP11B2IDO1TDO2LDHA
	SCHEMBL18015495	0.78	LDHA (0.50)	NPC1CYP11B1CYP11B2IDO1TDO2
	SCHEMBL19794370	0.78	LDHA (0.50)	NPC1CYP11B1CYP11B2IDO1TDO2
	SCHEMBL21721920	0.78	LDHA (0.50)	CYP11B1CYP11B2IDO1TDO2DHODH
	SCHEMBL19794431	0.78	LDHA (0.50)	NPC1CYP11B1CYP11B2IDO1TDO2
	SCHEMBL18015584	0.77	KDM4E (0.65)	NPC1IDO1TDO2SMN1; SMN2RAB9A
	SCHEMBL21125581	0.77	MEN1 (0.49)	NPC1HDAC6SMN1; SMN2RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.