Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015715 | 0.88 | LMNA (0.38) | L3MBTL1NPC1RAB9ADHODHLDHA | |
| SCHEMBL12668242 | 0.85 | L3MBTL1 (0.57) | L3MBTL1NPC1RAB9ADHODHLDHA | |
| SCHEMBL19794490 | 0.84 | MEN1 (0.49) | L3MBTL1NPC1RAB9ALDHAHPGDS | |
| SCHEMBL18015617 | 0.84 | MEN1 (0.49) | L3MBTL1LDHAHPGDSMAOAMAOB | |
| SCHEMBL18015531 | 0.82 | ADORA2A (0.38) | NPC1RAB9ALDHAHPGDSFEN1 | |
| SCHEMBL18538858 | 0.82 | L3MBTL1 (0.62) | L3MBTL1NPC1RAB9ADHODHLDHA | |
| SCHEMBL19794502 | 0.82 | MEN1 (0.42) | NPC1RAB9ALDHAHPGDSHSD17B1 | |
| SCHEMBL19794511 | 0.82 | FEN1 (0.38) | L3MBTL1NPC1LDHAHPGDSHSD17B1 | |
| SCHEMBL16526829 | 0.81 | L3MBTL1 (0.43) | L3MBTL1NPC1RAB9ACYP3A4KDR | |
| SCHEMBL21125581 | 0.81 | MEN1 (0.49) | NPC1RAB9ALDHAHPGDSHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | L3MBTL1 1661/4885NPC1 4039/4885RAB9A 2171/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | L3MBTL1 2863/4885NPC1 2761/4885RAB9A 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.