Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19795925 | 0.94 | ESRRG (0.40) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL19795961 | 0.90 | ALDH1A1 (0.43) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL19795949 | 0.87 | KMT2A (0.41) | KMT2AMEN1POLBTSHRALDH1A1 | |
| SCHEMBL19795905 | 0.86 | ALDH1A1 (0.42) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL19795935 | 0.85 | MLYCD (0.36) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL19041154 | 0.85 | KMT2A (0.38) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL19795955 | 0.83 | ALDH1A1 (0.40) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL19795947 | 0.83 | MAOB (0.50) | KMT2AMEN1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL19795899 | 0.82 | NPC1 (0.41) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL19796014 | 0.81 | HTT (0.41) | KMT2AMEN1TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | ERCC4, NQO1, ERCC5 | KMT2A 2823/4885MEN1 153/4885POLB 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.