Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19795961 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1KMT2AMEN1CES2 | |
| SCHEMBL19040948 | 0.82 | TSHR (0.38) | TSHRALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL19796002 | 0.81 | KMT2A (0.43) | TSHRALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL19795955 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1KMT2AMEN1CES2 | |
| SCHEMBL19795907 | 0.76 | CA12 (0.35) | ALDH1A1KMT2AMEN1CES2CES1 | |
| SCHEMBL19795974 | 0.76 | CES2 (0.45) | ALDH1A1KMT2APOLBMEN1RAB9A | |
| SCHEMBL19795949 | 0.75 | KMT2A (0.41) | TSHRALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL19795899 | 0.75 | NPC1 (0.41) | ALDH1A1KMT2APOLBMEN1RAB9A | |
| SCHEMBL19796012 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1RAB9ACES2 | |
| SCHEMBL19795923 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KMT2ARAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | ERCC4, NQO1, ERCC5 | TSHR 3898/4885ALDH1A1 981/4885KMT2A 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.