Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3543372 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPK1SMN1; SMN2TSHRHPGD | |
| SCHEMBL1989330 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2TSHRHPGD | |
| SCHEMBL8541716 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPK1SMN1; SMN2TSHRHPGD | |
| Hydrochloric Acid SCHEMBL10581422 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPK1SMN1; SMN2TSHRHPGD | |
| SCHEMBL19796043 | 0.81 | POLB (0.53) | ALDH1A1MAPK1SMN1; SMN2TSHRHPGD | |
| SCHEMBL12563886 | 0.78 | ALDH1A1 (0.35) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL62649 | 0.78 | KMT2A (0.41) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL31368629 | 0.78 | KMT2A (0.41) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL31368630 | 0.78 | KMT2A (0.41) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL21713101 | 0.76 | FABP3 (0.40) | ALDH1A1MAPK1SMN1; SMN2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104165-A1 | PYRIDINE[4,3-D]PYRIMIDINE COMPOUND AS TLR7/8 AGONIST | 上海维申医药有限公司 | 2023-06-15 | — | — | WO | disclosed |
| US-20180022710-A1 | ISOTOPOLOGUES OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE | SIGNAL PHARMACEUTICALS, LLC | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022710-A1 | ISOTOPOLOGUES OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TERT, NPY4R | ALDH1A1 1028/4885MAPK1 4281/4885SMN1; SMN2 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.