Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951802 | 0.81 | CSNK1A1 (0.50) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL8539809 | 0.81 | CYP4F2 (0.53) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL8614473 | 0.79 | CSNK1A1 (0.48) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL8537907 | 0.78 | CSNK1A1 (0.46) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL9665277 | 0.78 | CSNK1A1 (0.53) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL17304239 | 0.78 | CSNK1A1 (0.53) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL8538264 | 0.78 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL71453 | 0.77 | PTGER4 (0.68) | PTGER4PTGER3PTGER1PTGER2CCNC | |
| SCHEMBL8537580 | 0.76 | CSNK1A1 (0.44) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL8538742 | 0.76 | CYP1A2 (0.48) | CSNK1A1TYRO3DYRK1BMTORADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509981-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | Eli Lilly and Company (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071840-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | ELI LILLY AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |