SCHEMBL3054669

SCHEMBL3054669

Cc1ncn(C)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APOBEC3A P31941 4/20 0.42
▸ APOBEC3G Q9HC16 3/20 0.42
▸ BCAT2 O15382 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ KDM4E B2RXH2 3/20 0.36
▸ CTDSP1 Q9GZU7 2/20 0.36
▸ PKM P14618 2/20 0.36
▸ KDM2B Q8NHM5 2/20 0.35
▸ KDM4C Q9H3R0 2/20 0.35
▸ TDP1 Q9NUW8 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ ADORA2B P29275 1/20 0.33
▸ GPR35 Q9HC97 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23716719 0.98 APOBEC3A (0.41) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL19797901 0.81 APOBEC3A (0.41) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL23716720 0.79 APOBEC3A (0.40) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL67836 0.78 APOBEC3A (0.50) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL21879818 0.78 APOBEC3A (0.42) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL28220341 0.78 KDM4E (0.36) BCAT2LMNAHPGDKDM4EPKM
SCHEMBL25457959 0.78 APOBEC3A (0.46) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL25562761 0.78 APOBEC3A (0.39) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL21880074 0.77 APOBEC3A (0.41) APOBEC3AAPOBEC3GBCAT2LMNAHPGD
SCHEMBL14710278 0.77 APOBEC3A (0.41) APOBEC3AAPOBEC3GBCAT2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 — — US disclosed
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists BAYER AKTIENGESELLSCHAFT (DE) 2025-08-26 — — US disclosed
WO-2025037013-A1 DIAGNOSTIC COMPOUNDS THAT BIND TO ALPHA-SYNUCLEIN AC IMMUNE SA (CH) 2025-02-20 — — WO disclosed
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-14 — — US disclosed
US-12065430-B2 Indazole compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2024-08-20 — — US disclosed
US-20240270715-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-08-15 — — US disclosed
EP-4192813-B1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-08-14 — — EP disclosed
US-20240175141-A1 BIOBASED AND BIODEGRADABLE CORROSION INHIBITION COMPOSITION ZestBio, Inc. 2024-05-30 — — US disclosed
US-20240174685-A1 OX2R Compounds BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-05-30 — — US disclosed
EP-4058448-B1 HYDANTOIN DERIVATIVES AS ADAMTS7 ANTAGONISTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES BAYER AG (DE) 2024-05-29 — — EP disclosed
CN-1478080-A Phenylethenyl or phenylethinyl derivatives as glutamate receptor antagonists - 2004-02-25 — — CN disclosed
US-20030225070-A1 Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles MUTEL VINCENT (FR) 2003-12-04 — — US disclosed
US-20030208082-A1 Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles MUTEL VINCENT (FR) 2003-11-06 — — US disclosed
EP-1349839-A1 PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2003-10-08 — — EP disclosed
US-20020128263-A1 Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles F.HOFFMANN-LA ROCHE AG (CH) 2002-09-12 — — US disclosed
WO-2002046166-A1 PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2002-06-13 — — WO disclosed
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 — — EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 — — US disclosed
CN-1122333-A Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 1996-05-15 — — CN disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065430-B2 Indazole compound or salt thereof RCOR3, H1-3, BICRA APOBEC3A 3280/4885APOBEC3G 3381/4885BCAT2 1094/4885
US-20240174685-A1 OX2R Compounds HCRTR2, HCRTR1, OXTR APOBEC3A 2302/4885APOBEC3G 1896/4885BCAT2 1498/4885
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 APOBEC3A 4166/4885APOBEC3G 3184/4885BCAT2 292/4885
US-20030208082-A1 Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles GRM5, GRIK5, GRM1 APOBEC3A 4775/4885APOBEC3G 4756/4885BCAT2 1526/4885
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists ADAMTS7, MMP7, ADAM17 APOBEC3A 545/4885APOBEC3G 602/4885BCAT2 1970/4885
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB APOBEC3A 3664/4885APOBEC3G 2901/4885BCAT2 866/4885
US-20020128263-A1 Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles GRM5, GRIK5, GRM1 APOBEC3A 4775/4885APOBEC3G 4756/4885BCAT2 1526/4885
US-20240270715-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 APOBEC3A 4166/4885APOBEC3G 3184/4885BCAT2 292/4885
US-20030225070-A1 Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles GRM5, GRIK5, HRH4 APOBEC3A 4643/4885APOBEC3G 4668/4885BCAT2 1140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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