Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.40 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798489 | 0.88 | PDGFRB (0.43) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL30963226 | 0.84 | DGAT1 (0.44) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL17464375 | 0.84 | DGAT1 (0.44) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL29604376 | 0.82 | GSK3A (0.42) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL21198942 | 0.82 | GSK3A (0.42) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL19100726 | 0.81 | PDGFRB (0.43) | GSK3AGSK3BSMN1; SMN2PDGFRBKDR | |
| SCHEMBL16077123 | 0.81 | DGAT1 (0.40) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL20766929 | 0.79 | CXCR2 (0.52) | SMN1; SMN2PDGFRBKDRLIPGCA1 | |
| SCHEMBL17419204 | 0.78 | GSK3A (0.39) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL30551407 | 0.77 | LPL (0.38) | GSK3AGSK3BPDGFRBKDRDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022723-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022723-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | HAVCR2, HCCS, SLC10A1 | GSK3A 1668/4885GSK3B 1395/4885SMN1; SMN2 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.