Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21198942 | 1.00 | GSK3A (0.42) | GSK3AGSK3BUCHL1KDM4EDGAT1 | |
| SCHEMBL17464375 | 0.86 | DGAT1 (0.44) | GSK3AGSK3BUCHL1DGAT1PDGFRB | |
| SCHEMBL30963226 | 0.86 | DGAT1 (0.44) | GSK3AGSK3BUCHL1DGAT1PDGFRB | |
| SCHEMBL21199644 | 0.84 | KDM4E (0.47) | GSK3AGSK3BUCHL1KDM4EDGAT1 | |
| SCHEMBL3450902 | 0.83 | AAK1 (0.40) | GSK3AGSK3BUCHL1DGAT1ALDH1A1 | |
| SCHEMBL16077123 | 0.83 | DGAT1 (0.40) | GSK3AGSK3BDGAT1PDGFRBKDR | |
| SCHEMBL19797952 | 0.82 | GSK3A (0.41) | GSK3AGSK3BDGAT1PDGFRBKDR | |
| SCHEMBL3798489 | 0.82 | PDGFRB (0.43) | GSK3AGSK3BKDM4EDGAT1PDGFRB | |
| SCHEMBL3448994 | 0.80 | UCHL1 (0.38) | GSK3AGSK3BUCHL1DGAT1ALDH1A1 | |
| SCHEMBL3449126 | 0.80 | GSK3A (0.36) | GSK3AGSK3BUCHL1KDM4EDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983074-A1 | PYRIDINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |