⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505218 | 0.87 | CYP19A1 (0.33) | — | |
| SCHEMBL1978579 | 0.86 | — | — | |
| SCHEMBL1978763 | 0.83 | CYP19A1 (0.31) | — | |
| SCHEMBL3126659 | 0.83 | — | — | |
| SCHEMBL145955 | 0.79 | — | — | |
| SCHEMBL1955612 | 0.79 | CYP19A1 (0.36) | — | |
| SCHEMBL516934 | 0.78 | — | — | |
| SCHEMBL1250812 | 0.76 | — | — | |
| SCHEMBL16242856 | 0.76 | MAOA (0.32) | — | |
| SCHEMBL155171 | 0.76 | SPHK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328126-B2 | Norbornenylhydrocarbylene dihydrocarbylboranes and methods of making the same | PROMERUS, LLC (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150353582-A1 | NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME | PROMERUS, LLC (US) | 2015-12-10 | — | — | US | disclosed |
| WO-2014121008-A1 | NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME | PROMERUS, LLC (US) | 2014-08-07 | — | — | WO | disclosed |
| US-8765894-B2 | Norbornene-type polymers having quaternary ammonium functionality | PROMERUS, LLC (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765893-B2 | Norbornene-type polymers having quaternary ammonium functionality | PROMERUS, LLC (US) | 2014-07-01 | — | — | US | disclosed |
| EP-2510036-A2 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | Promerus LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20110244368-A1 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110143260-A1 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-06-16 | — | — | US | disclosed |
| WO-2011072304-A2 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-06-16 | — | — | WO | disclosed |
| US-4931495-A | FREE RADICAL POLYMERIZATION OF UNSATURATED CARBOXYLIC ACIDS OR ESTERS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0308146-A2 | Non-aqueous dispersion polymerization | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4085168-A | STABILIZERS, FLOCCULANTS, HYDROGELS, THICKENERS, ION EXCHANGE RESINS, DRILLING MUDS | CPC INTERNATIONAL INC. (US) | 1978-04-18 | — | — | US | disclosed |