Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535957 | 0.83 | EPHX1 (1.00) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| SCHEMBL4542363 | 0.82 | EPHX1 (1.00) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| SCHEMBL18028792 | 0.78 | EPHX1 (0.49) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| SCHEMBL4539949 | 0.78 | EPHX1 (0.55) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| SCHEMBL4537511 | 0.78 | EPHX1 (0.84) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| Hydrochloric Acid SCHEMBL18686528 | 0.78 | EPHX1 (0.64) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| Hydrochloric Acid SCHEMBL18686624 | 0.78 | EPHX1 (0.64) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| Hydrochloric Acid SCHEMBL18686525 | 0.78 | EPHX1 (0.64) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| SCHEMBL12196135 | 0.77 | EPHX1 (1.00) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| SCHEMBL4542890 | 0.77 | EPHX1 (0.53) | EPHX1ALDH1A1EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | IDO1, IDO2, TDO2 | EPHX1 1923/4885ALDH1A1 2128/4885MAPT 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.