Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798447 | 0.78 | EPHX1 (0.71) | EPHX1ALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL12987764 | 0.72 | EPHX2 (0.48) | EPHX1EPHX2 | |
| SCHEMBL14269955 | 0.70 | EPHX2 (0.38) | EPHX1KMT2AEPHX2 | |
| SCHEMBL22309428 | 0.69 | FAAH (0.50) | EPHX1ALDH1A1MAPTKMT2AEPHX2 | |
| SCHEMBL8042539 | 0.67 | EPHX2 (0.45) | EPHX1ALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL17425868 | 0.66 | GRIN2D (0.41) | — | |
| SCHEMBL19577536 | 0.65 | EPHX1 (0.47) | EPHX1HPGDKMT2AEPHX2 | |
| SCHEMBL4535957 | 0.64 | EPHX1 (1.00) | EPHX1ALDH1A1MAPTNPSR1KMT2A | |
| SCHEMBL18720724 | 0.64 | EPHX2 (0.40) | EPHX1ALDH1A1HPGDKMT2AEPHX2 | |
| SCHEMBL5994123 | 0.64 | ALDH1A1 (0.50) | EPHX1ALDH1A1MAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016131380-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO.,LTD. (CN) | 2016-08-25 | — | — | WO | disclosed |