Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933094 | 0.90 | ESR1 (0.52) | THRATHRBESR1CYP19A1MAPT | |
| SCHEMBL2249192 | 0.90 | ESR1 (0.52) | THRATHRBESR1CYP19A1MAPT | |
| SCHEMBL28091947 | 0.86 | MAPT (0.48) | THRATHRBMAPTLMNANPSR1 | |
| SCHEMBL9322138 | 0.82 | THRA (0.54) | THRATHRBESR1CYP19A1MAPT | |
| SCHEMBL28081960 | 0.81 | MAPT (0.48) | CYP19A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL11229570 | 0.80 | THRA (0.50) | THRATHRBESR1CYP19A1MAPT | |
| SCHEMBL28401823 | 0.80 | MAPT (0.47) | THRATHRBESR1CYP19A1MAPT | |
| SCHEMBL11245167 | 0.80 | ALDH1A1 (0.40) | MAPTSMN1; SMN2L3MBTL1PRSS1GAA | |
| SCHEMBL862599 | 0.79 | ESR1 (0.51) | THRATHRBESR1MAPTLMNA | |
| SCHEMBL13475563 | 0.79 | ESR1 (0.51) | THRATHRBESR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180026192-A1 | POLYMER AND ORGANIC SOLAR CELL COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-01-25 | — | — | US | disclosed |