Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358085 | 0.91 | MAPT (0.51) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL11229570 | 0.91 | THRA (0.50) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL9322159 | 0.88 | THRA (0.48) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL2249192 | 0.88 | ESR1 (0.52) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL6933094 | 0.88 | ESR1 (0.52) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL11221682 | 0.86 | THRA (0.49) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL8888172 | 0.86 | THRB (0.49) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL11581876 | 0.86 | MAPT (0.49) | THRATHRBPLA2G4BESR1MAPT | |
| SCHEMBL8358231 | 0.83 | MAPT (0.57) | THRATHRBPLA2G4BMAPTLMNA | |
| SCHEMBL7786961 | 0.83 | CYP19A1 (0.60) | THRATHRBPLA2G4BMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402688-B1 | 1,3-Di-arylmethoxy-4,6-dinitrobenzenes, process for their preparation and process for preparing 4,6-diaminoresorcin | BAYER AG (DE) | 1994-02-16 | — | — | EP | claimed |
| US-5072053-A | Monomers for polybenzoxazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | claimed |
| JP-3024038-A | — | — | None | — | — | JP | disclosed |
| EP-0402688-B1 | 1,3-Di-arylmethoxy-4,6-dinitrobenzenes, process for their preparation and process for preparing 4,6-diaminoresorcin | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |
| US-5072053-A | Monomers for polybenzoxazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| US-5072053-A | Monomers for polybenzoxazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| JP-H0324038-A | 1,3-ARYLMETHOXY-4,6-DINITRO-BENZENE, ITS PRODUCTION AND PRODUCTION OF 4,6-DIAMINORESORCINOL | BAYER AG | 1991-02-01 | — | — | JP | disclosed |
| EP-0402688-A2 | 1,3-Di-arylmethoxy-4,6-dinitrobenzenes, process for their preparation and process for preparing 4,6-diaminoresorcin | BAYER AG (DE) | 1990-12-19 | — | — | EP | disclosed |
| EP-0402688-A2 | 1,3-Di-arylmethoxy-4,6-dinitrobenzenes, process for their preparation and process for preparing 4,6-diaminoresorcin | BAYER AG (DE) | 1990-12-19 | — | — | EP | disclosed |