Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19792826 | 0.93 | FDPS (0.43) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL19792816 | 0.76 | FDPS (0.67) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL7858714 | 0.75 | FDPS (0.47) | FDPSGGPS1LMNABTN3A1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL4951600 | 0.70 | FDPS (0.47) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL8843613 | 0.70 | FDPS (0.51) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL3978401 | 0.69 | FDPS (0.58) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL422099 | 0.68 | CYP11B1 (0.50) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL7852810 | 0.68 | FDPS (0.49) | FDPSGGPS1LMNABTN3A1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL4952771 | 0.68 | FDPS (0.49) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL26803165 | 0.67 | FDPS (0.42) | FDPSGGPS1LMNABTN3A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280188-B2 | Fluorine-containing bisphosphonic acid derivative and use thereof | NAGASAKI UNIVERSITY (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20180022769-A1 | NOVEL FLUORINE-CONTAINING BISPHOSPHONIC ACID DERIVATIVE AND USE THEREOF | NAGASAKI UNIVERSITY (JP) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280188-B2 | Fluorine-containing bisphosphonic acid derivative and use thereof | CD4, CD22, CD69 | FDPS 1193/4885GGPS1 2075/4885LMNA 4097/4885 |
| US-20180022769-A1 | NOVEL FLUORINE-CONTAINING BISPHOSPHONIC ACID DERIVATIVE AND USE THEREOF | CD4, CD22, CD69 | FDPS 1472/4885GGPS1 2069/4885LMNA 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.