Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852810 | 0.88 | FDPS (0.49) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL8843613 | 0.77 | FDPS (0.51) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL19799422 | 0.75 | FDPS (0.46) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL10468127 | 0.72 | MAPT (0.37) | LMNAALDH1A1 | |
| SCHEMBL19792826 | 0.72 | FDPS (0.43) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL7853015 | 0.69 | FDPS (0.66) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL9716426 | 0.69 | TBXAS1 (0.52) | FDPSLMNATBXAS1EGLN3 | |
| Diethyl Hydrogen Phosphate SCHEMBL4951600 | 0.67 | FDPS (0.47) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL563845 | 0.67 | ALDH1A1 (0.56) | TBXAS1ALDH1A1ABL1RIN1EGLN3 | |
| SCHEMBL4903214 | 0.66 | MAPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788362-B1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 2001-07-25 | — | — | EP | disclosed |
| US-5760021-A | TREATING OR PREVENTING METABOLIC BONE DISORDERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0788362-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1993024131-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |